The most common cause of genetic neuropathy, classified as Charcot-Marie-Tooth disease, is a 1.4 Mb duplication of the PMP22 gene.
John Svaren
John Svaren honored with Vilas professorship
Professor of Comparative Biosciences at the School of Veterinary Medicine and Waisman Center investigator, John Svaren, PhD, is a recipient of a Vilas Distinguished Professorship.
Waisman’s Own Takes Interim Position in OVCRGE
CMT is a slowly progressive disease in contrast to ALS, which affects the same neurons in the peripheral nervous system.
John Svaren joins research office leadership team
John Svaren, professor of Comparative Biosciences at the School of Veterinary Medicine and director of the Waisman Center IDD Models Core, has been named the interim Associate Vice Chancellor for Research in the Biological Sciences.
John Svaren, PhD – Slide of the Week
Schwann cells play a critical role after peripheral nerve injury by clearing myelin debris, forming axon-guiding bands of Büngner, and remyelinating regenerating axons.
In the lab where sign language advances science: A spotlight on Phu Duong
Epigenetics – the study of how environment can change and affect how genes function – was a new field for Phu Duong, PhD.
Cells with a superhero alter ego: Schwann cells transform into repair cells after nerve injury with help of transcription factor JUN and Sonic Hedgehog gene
When nerves are injured, Schwann cells—a key cell in peripheral nerve function and nerve insulation—assume a new role and identity as repair cells.
John Svaren, PhD – Slide of the Week
The goal of this proposal was to determine if microRNA’s (miR) are elevated in the plasma of individuals affected by the inherited peripheral neuropathy Charcot-Marie-Tooth Disease, type 1A (CMT1A)
CMT biomarkers for future treatments
A new test may spur advances in drug discovery for a rare and debilitating neurological disorder. Charcot-Marie-Tooth disease, a rare inherited neurological disorder, affects more than 2.8 million people around the globe.
CMT advocate will not be sidelined
CMT is equally common among all ages, genders, and races and is one of the most common heritable neurological impairments. The symptoms present as neuropathy, foot drop, poor balance, difficulty with dexterity, or abnormal sensation – just to name a few.