Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Formation of myelin by Schwann cells is tightly coupled to peripheral nervous system development and is important for neuronal function and long-term maintenance.
Our brain is big on team work makes the dream work. Not only brain cells, but even smaller units that make up a cell work in cooperation to make the brain work properly.
The most common cause of genetic neuropathy, classified as Charcot-Marie-Tooth disease, is a 1.4 Mb duplication of the PMP22 gene.
Professor of Comparative Biosciences at the School of Veterinary Medicine and Waisman Center investigator, John Svaren, PhD, is a recipient of a Vilas Distinguished Professorship.
CMT is a slowly progressive disease in contrast to ALS, which affects the same neurons in the peripheral nervous system.
John Svaren, professor of Comparative Biosciences at the School of Veterinary Medicine and director of the Waisman Center IDD Models Core, has been named the interim Associate Vice Chancellor for Research in the Biological Sciences.
Schwann cells play a critical role after peripheral nerve injury by clearing myelin debris, forming axon-guiding bands of Büngner, and remyelinating regenerating axons.
Epigenetics – the study of how environment can change and affect how genes function – was a new field for Phu Duong, PhD.
When nerves are injured, Schwann cells—a key cell in peripheral nerve function and nerve insulation—assume a new role and identity as repair cells.
The goal of this proposal was to determine if microRNA’s (miR) are elevated in the plasma of individuals affected by the inherited peripheral neuropathy Charcot-Marie-Tooth Disease, type 1A (CMT1A)
