Title: Altered flip/flop alternative splicing causes a reduction of the decay time constant of the AMPA receptor. Legend: (a) RNA-Seq analysis reveals a significant change of the relative flip/flop ratio of Gria2 in Mecp2 KO …
Month: September 2016
Lighting up the search for a therapy for fragile X syndrome
Waisman Center researchers Anita Bhattacharyya and Xinyu Zhao are looking to make stem cells glow. That glow will tell them that they have successfully turned on a gene that is usually turned off in individuals …
Pelin Cengiz, MD – Slide of the Week
Title: ERα Signaling Is Required for TrkB-Mediated Hippocampal Neuroprotection in Female Neonatal Mice after Hypoxic Ischemic Encephalopathy Legend: Increases in p-TrkB immuno and protein expressions are sexually differentiated and ERα dependent post-HI. A. Changes in …
Study finds a key to nerve regeneration
Researchers at the University of Wisconsin–Madison have found a switch that redirects helper cells in the peripheral nervous system into “repair” mode, a form that restores damaged axons. Axons are long fibers on neurons that …
Anita Bhattacharyya, PhD
Title: Creation of a human reporter stem cell line for detecting fragile X mental retardation (FMR1) gene reactivation in human neural cells. Legend: Fragile X syndrome (FXS) is the most common inherited cause of intellectual …