CMT is a slowly progressive disease in contrast to ALS, which affects the same neurons in the peripheral nervous system.
Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease, and retinitis pigmentosa all have different manifestations and affect different body functions, but they are all connected by one mechanism: neurodegeneration.
John Svaren, professor of Comparative Biosciences at the School of Veterinary Medicine and director of the Waisman Center IDD Models Core, has been named the interim Associate Vice Chancellor for Research in the Biological Sciences.
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When nerves are injured, Schwann cells—a key cell in peripheral nerve function and nerve insulation—assume a new role and identity as repair cells.
A new test may spur advances in drug discovery for a rare and debilitating neurological disorder. Charcot-Marie-Tooth disease, a rare inherited neurological disorder, affects more than 2.8 million people around the globe.
A new study from the lab of UW-Madison professor of medicine Luigi Puglielli, MD, PhD, opens a door to potential treatments for diseases of age, such as Alzheimer’s disease, by defining the roles of two enzymes that are imperative to protein production.
CMT is equally common among all ages, genders, and races and is one of the most common heritable neurological impairments. The symptoms present as neuropathy, foot drop, poor balance, difficulty with dexterity, or abnormal sensation – just to name a few.
Researchers at the University of Wisconsin–Madison have found a switch that redirects helper cells in the peripheral nervous system into “repair” mode, a form that restores damaged axons. Axons are long fibers on neurons that …
Every day, Waisman Center researcher John Svaren deals with nerves – peripheral nerves, that is. Peripheral nerves connect the brain and spinal cord to our limbs and organs, serving as vital communication relays that allow …