Neurodegeneration research at the Waisman Center from gene to organelle to cell to brain

Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease, and retinitis pigmentosa all have different manifestations and affect different body functions, but they are all connected by one mechanism: neurodegeneration.

Cells with a superhero alter ego: Schwann cells transform into repair cells after nerve injury with help of transcription factor JUN and Sonic Hedgehog gene

When nerves are injured, Schwann cells—a key cell in peripheral nerve function and nerve insulation—assume a new role and identity as repair cells.