Understanding cell-type-specific gene regulatory mechanisms from genetic variants to diseases remains challenging. To address this, we developed a computational pipeline, scGRNom (single-cell Gene Regulatory Network prediction from multi-omics), to predict cell-type disease genes and regulatory networks including transcription factors and regulatory elements.
Month: June 2021
Houri K. Vorperian, PhD – Slide of the Week
Title: Auditory-Perceptual Features of Speech in Children and Adults with Down syndrome: A Speech Profile Analysis Legend: Table 6 – Principal component loading matrix, first four principal components, vowel features. Note. The largest loadings (in …
UCEDD project to address health equity for Latino families of children with developmental disabilities
Padres e Hijos en Acción and the Waisman Center UCEDD announced a $330,000 grant to improve local health care responsiveness to the needs of Latino families of children with developmental disabilities and other special health care needs in Dane County.
Brittany G. Travers, PhD – Slide of the Week
Title: Associations among daily living skills, motor, and sensory difficulties in children with and without autism Legend: The goal of this study was to determine how motor skills relate to daily living skills in children 6-10 …
John Svaren, PhD – Slide of the Week
Title: CRISPR-Cas9 deletion of PMP22 super enhancer creates a new model of hereditary neuropathy with liability to pressure palsies (HNPP) Legend: (A) Morphometric analysis demonstrates axonal loss i thin section were taken from 3- to 5-month-old …