Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Inhibitory control (IC) develops in stages from infancy through adolescence and is associated with numerous developmental disorders and learning outcomes.
Asthma, a highly prevalent chronic inflammatory disease of the airways, results in an average of 10 deaths per day in the U.S., and psychological stress hinders its effective management.
Female monkeys were vaccinated with spike protein from the ancestral virus (Wuhan) or an early variant (Gamma). Their infants had high levels of maternal IgG at birth, which more specifically inhibited the virus against which their mother had been immunized.
Adults with Down syndrome demonstrate striatum-first amyloid accumulation with [11C]Pittsburgh Compound-B (PiB) positron emission tomography (PET) imaging, which has not been replicated with [18F]florbetapir (FBP). Early striatal accumulation has not been temporally quantified with respect to global cortical measures.
TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury
Basal forebrain cholinergic neurons (BFCNs) are integral to learning, attention, and memory, and are prone to degeneration in Down syndrome (DS), Alzheimer's disease, and other neurodegenerative diseases.
The gut microbiome is a potentially modifiable risk factor for Alzheimer's disease (AD); however, understanding of its composition and function regarding AD pathology is limited.
Neurite initiation from newly born neurons is a critical step in neuronal differentiation and migration.
How do infants become word meaning experts? This registered report investigated the structure of infants' early lexical representations by manipulating the typicality of exemplars from familiar animal categories.
Disciplines across the social and behavioral sciences have documented the critical role of early peer connections in children's development, yet mechanisms facilitating these connections have not been tested in controlled laboratory settings.
