Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Children born preterm are at an elevated risk of language delays compared to children born full-term.
Re-expression of Halo-TSC2 for 1 DIV in TSC2-/- cortical neurons reduces hyper-phosphorylated S6 and increased neurite length
Listeners had increased levels of fatigue when they heard dysarthric speech relative to non-dysarthric speech.
Mean physical and behavioral depressive symptoms on the Reiss Screen of Maladaptive Behavior (RSMB) across four data collection cycles in sample of 262 adults with Down syndrome. Blue line is for those with low PET amyloid and green line for those with elevated PET amyloid.
Title: Congruent gene expression in Alexander disease model mice and human Alzheimer’s disease Legend: (A) A Rank-Rank Hypergeometric Overlap (RRHO) heatmap comparing a composite gene expression portrait of human Alzheimer’s disease (AD, X axis) with transcriptomic changes in hippocampus from Alexander disease model mice (GFAP mutation, Y axis) indicates high matching of up- and downregulated …
Processing neural activity to reconstruct network connectivity is a central focus of neuroscience, yet the spatiotemporal requisites of biological nervous systems are challenging for current neuronal sensing modalities.
Processing neural activity to reconstruct network connectivity is a central focus of neuroscience, yet the spatiotemporal requisites of biological nervous systems are challenging for current neuronal sensing modalities.
Evidence-based assessment pathways inform early detection of cerebral palsy and access to intervention.
Autistic children experience high rates of feeding challenges, negatively affecting their health, eating patterns, and social eating experiences.
Probing how human neural networks operate is hindered by the lack of reliable human neural tissues amenable to the dynamic functional assessment of neural circuits.
