Height is a highly heritable, classic polygenic trait with approximately 700 commonly associated variants identified through genome-wide association studies so far.
Slide of the Week
Barbara Bendlin, PhD
Myelin and myelin-producing oligodendrocytes appear to be affected in Alzheimer’s disease (AD), but this is understudied in humans, particularly in the early stages of disease development.
Karla Ausderau, PhD
Objective – Identify and describe parents’ strategies used to support mealtime participation for their child with autism spectrum disorder (ASD).
Andrew Alexander, PhD
Mapping White Matter Microstructure in the One Month Human Brain Legend: Matched coronal and axial slices through the of the population averaged diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) parameters …
Luigi Puglielli, MD, PhD
Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation Legend: AT-1 Tg animals display changes in neuronal morphology and imbalanced synaptic plasticity. (A-D) Morphological assessment of hippocampal neurons …
Xinyu Zhao, PhD
Integrative Single-Cell Transcriptomics Reveal Molecular Networks Defining Neuronal Maturation during Postnatal Neurogenesis Legend: Left: An illustration of coronal section of Nissl-stained adult mouse brain; Confocal images showing that most of DsRed+ (red) cells in DCX-dsRed …
Su-Chun Zhang, MD, PhD
Alexander disease patient astrocytes have impaired calcium wave propagation Legend: A) Still images over time from mechanical stimulation of 6-month astrocytes loaded with Fluor-4AM and accompanying post-experiment GFAP stains. B) Average duration of increased calcium …
Houri Vorperian, PhD
We present a registration-based semi-automatic mandible segmentation (SAMS) pipeline designed to process a large number of computed tomography studies to segment three dimensional (3D) mandibles.
John Svaren, PhD
Peripheral nerve regeneration after injury is dependent upon implementation of a novel genetic program in Schwann cells that supports axonal survival and regeneration.
Masatoshi Suzuki, DVM, PhD
Our current research is to apply stem cell technology to disease modeling and therapeutic applications for neuromuscular diseases such as ALS (also known as Lou Gehrig’s disease).