Adversity during infancy can affect neurobehavioral development and perturb the maturation of physiological systems. Dysregulated immune and inflammatory responses contribute to many of the later effects on health.
Slide of the Week
Andrew McVea, MS, (Christian Lab) – Slide of the Week
Earlier beta-amyloid (Aβ) plaque accumulation and a higher prevalence of Alzheimer’s Disease is seen in the Down syndrome (DS) population due to the triplication of chromosome 21 containing the amyloid precursor protein (APP) gene.
Anita Bhattacharyya, PhD – Slide of the Week
Formation of synapses, the connections among nerve cells, is a critical process in brain development.
Carlos Benítez-Barrera, PhD – Slide of the Week
The neural correlates of predictive processing in language, critical for efficient sentence comprehension, is well documented in adults.
Andrew Alexander, PhD – Slide of the Week
This investigation explores memory performance using the California Verbal Learning Test in relation to morphometric and connectivity measures of the memory network in severe traumatic brain injury.
Erik W. Dent, PhD – Slide of the Week
Dendritic spines, the mushroom-shaped extensions along dendritic shafts of excitatory neurons, are critical for synaptic function and are one of the first neuronal structures disrupted in neurodevelopmental and neurodegenerative diseases.
Xinyu Zhao, PhD – Slide of the Week
Fragile X messenger ribonucleoprotein 1 protein (FMRP) deficiency leads to fragile X syndrome (FXS), an autism spectrum disorder.
Donna Werling, PhD – Slide of the Week
DNA libraries generated from 235 post mortem human brain samples were sequenced using 150 bp, paired end Illumina chemistry to a desired depth of 30X coverage. Reads were aligned to either the linear GRCh38 alt-free reference genome, the linear telomere to telomere hs1 reference genome, or the draft human pangenome.
Daifeng Wang, PhD – Slide of the Week
Genotypes are strongly associated with disease phenotypes, particularly in brain disorders. However, the molecular and cellular mechanisms behind this association remain elusive.
Brittany G. Travers, PhD – Slide of the Week
We want to better understand how autistic children with and without attention-deficit/hyperactivity disorder (ADHD) differed in their motor skills, sensory features, and daily living skills.