Patient-derived induced stem cells retain disease traits
When neurons started dying in Clive Svendsen’s lab dishes, he couldn’t have been more pleased.
Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
When neurons started dying in Clive Svendsen’s lab dishes, he couldn’t have been more pleased.
There are many ways to die, but amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease must be one of the worst.
Research at UW-Madison has already shown that meditation can change the brain. Now a new grant will allow a more in-depth investigation of how these changes can affect sleep, pain tolerance, emotion regulation and other measures of well-being.
“Don’t give up, my love, or I’ll give up with you, because I only live to see the fulfillment of this dream: that you may continue to live. Yours is a life sentence, not a death sentence.”
“The novelty is that this is a combined cell and gene therapy approach,” Suzuki explains, noting that the bone marrow stem cells on their own had a modest effect, possibly by releasing their own protective factors. “But only when we engineered the cells to release GDNF did we see a significant improvement. The cells turned out to be quite an important component. It’s this combination of cells and drug delivery that seems to be so effective.”
By Brian Mattmiller, University Communications What is happening in the minds of people who have developed a greater capacity for forgiveness and compassion? Can a quality like love — whether it’s shown toward a family member or a friend — be neurologically measured in the brain? A new research project at UW–Madison offers the opportunity to apply …
Some of Madison’s most precious assets are deep-frozen in vials at University Research Park. The National Stem Cell Bank, the country’s only official repository of human embryonic stem cells, is housed at the WiCell Research Institute, a nonprofit organization affiliated with UW-Madison.
Getting a good job as a teenager can be difficult enough, let alone when the teenage job-seeker has a disability such as autism.
Stimulant medications such as Ritalin have been prescribed for decades to treat attention deficit hyperactivity disorder (ADHD), and their popularity as “cognition enhancers” has recently surged among the healthy, as well.
Outgoing Chancellor John D. Wiley has been named the new interim director of the Wisconsin Institute for Discovery (WID), the public half of the new research center that promises to be a model of interdisciplinary science and public-private collaboration.