Adults with Down syndrome demonstrate striatum-first amyloid accumulation with [11C]Pittsburgh Compound-B (PiB) positron emission tomography (PET) imaging, which has not been replicated with [18F]florbetapir (FBP). Early striatal accumulation has not been temporally quantified with respect to global cortical measures.
Down syndorme
BuILD Study (Brain Imaging and Language Development in Infants with Down Syndrome) (Dean)
Recruiting parents of children with Down Syndrome who are between 1 and 24 months old.
Hypoglossal Nerve Stimulator Study (Stanley)
We are studying new ways to treat obstructive sleep apnea in children and young adults with Down syndrome who have persistent obstructive sleep apnea despite prior tonsillectomy.
What research has revealed about Down syndrome’s influence on brain development
A new review paper published in Nature Reviews Neuroscience from Bhattacharyya, associate professor of cell and regenerative biology, pulls together what is currently known about DS’s impact on brain development.