Category: Down Syndrome

Down syndrome poster fair and research symposium will honor the Dewey family

The two-day event will take place at the Waisman Center on Thursday, November 5 and Friday, November 6.

Ann Dewey Catalyst Fund helps launch major NIH grant to advance Down syndrome research

Research funding that supports early-stage ideas plays a critical role in advancing scientific discovery.  A new National Institutes of Health (NIH) grant awarded to Waisman investigator André Sousa, PhD, associate professor of neuroscience at the UW–Madison, demonstrates how strategic seed funding can lay the groundwork for transformative research. Sousa recently received a five-year multimillion-dollar grant …

New drug shows promise for treating Down syndrome-related brain changes

Individuals with Down syndrome have differences in how their brains form that cause intellectual disability. Down syndrome or trisomy 21 is the most common genetic cause of intellectual and developmental disability and is caused by the triplication of chromosome 21.

Lawrence University senior takes on language development research at Waisman

Giang Pham, a rising senior from Lawrence University in Appleton, is spending her second summer doing research at the Waisman Center University of Wisconsin–Madison as part of an internship program established and supported by the late John Mielke, MD, a former member of the Waisman Board of Visitors and Appleton native, and his wife Sally. …

Puerto Rico to become a site for The Alzheimer Biomarker Consortium – Down syndrome

Puerto Rican families have started traveling to Wisconsin to be part of the research study, but the goal is to build the infrastructure to eventually conduct the studies on the island.

Changes in walking patterns could be an important new screening tool for Alzheimer’s in individuals with Down syndrome

Individuals with Down syndrome have a 90% lifetime risk of developing Alzheimer’s disease.

Earliest signs of neurodegeneration in Down syndrome detected shortly after birth, new Waisman study shows

Signs of neurodegeneration in individuals with Down syndrome may start as early as birth, a critical stage of brain development, a new study shows. The research, from investigators at the Waisman Center, University of Wisconsin-Madison, provides an atlas of early brain development in Down syndrome that could inform potential targeted treatments to address the developmental and degenerative aspects of the condition.

Developmental markers have the potential to make diagnosing autism in individuals with Down syndrome easier

Down syndrome, a neurodevelopmental condition caused by a triplicated 21st chromosome, often presents with co-occurring developmental conditions such as autism. But diagnosing autism in someone with Down syndrome can be difficult as they have overlapping symptoms.

Early adversity strongly predicts adult mental health challenges in people with Down syndrome, new study finds

A new Waisman study found that adverse childhood experiences (ACEs)—such as abuse, neglect, or exposure to household challenges—can have lasting effects on adults with Down syndrome, including their mental health and ability to cope with life changes. While ACES are known to impact the general population, this research is among the first to show similar—and in some cases heightened—effects in individuals with Down syndrome.

Wisconsin LEND trainees visit state legislators to share their personal stories and educate about the impact of Medicaid on Wisconsinites with disabilities

The Wisconsin LEND Program prepares individuals with disabilities to engage in policy discussions, giving them the tools and confidence to make their voices heard.