The appearance of cognitive deficits in infancy suggests that alterations emerge during the earliest stages of neural development and continue throughout the lifespan in DS.
Neurogenesis
André Sousa, PhD – Slide of the Week
Title: Single-cell gene expression analysis reveals signatures of adult neurogenesis in mouse, pig and macaque, but not in humans. Legend: A) Schematic of the analytic workflow. DG: dentate gyrus; CA: cornu ammonis; Sub: subiculum; EC: entorhinal …
Single brain cells reveal genes controlling formation, development
In one of the first studies to “read” the genetic activity inside individual brain cells, University of Wisconsin—Madison neuroscientist Xinyu Zhao has identified the genetic machinery that causes maturation in a young nerve cell.