Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Astrogliosis following hypoxia-ischemia (HI) related brain injury plays a role in increased morbidity and mortality in neonates. Recent clinical studies indicate that the severity of brain injury appears to be sex-dependent and that male neonates are more susceptible to the effects of HI resulting in worse neurological outcomes compared to females with comparable brain injuries.
Height is a highly heritable, classic polygenic trait with approximately 700 commonly associated variants identified through genome-wide association studies so far.
Myelin and myelin-producing oligodendrocytes appear to be affected in Alzheimer’s disease (AD), but this is understudied in humans, particularly in the early stages of disease development.
Objective – Identify and describe parents’ strategies used to support mealtime participation for their child with autism spectrum disorder (ASD).
Waisman Biomanufacturing and Waisman affiliate investigators Randolph Ashton and Krishanu Saha will be part of a new engineering research center that will develop transformative tools and technologies for the consistent, scalable and low-cost production of high-quality living therapeutic cells. Such cells could be used in a broad range of life-saving medical therapies now emerging from …
Mapping White Matter Microstructure in the One Month Human Brain Legend: Matched coronal and axial slices through the of the population averaged diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) parameters (Left). Gestation corrected age relationships of fractional anisotropy (FA), radial diffusivity (RD) and neurite density (νIC) for left hemisphere white …
A Q&A with new Waisman Center investigator Lauren Bishop-Fitzpatrick. How did you get into your field of research? Like many people who pursue social work degrees, I always knew that I wanted to spend my career helping others. Although I first volunteered with children with autism when I was 15, it was not until I took …
As rates of autism diagnoses rise across the country, children with autism and their parents also have increasing options for therapy and treatments. The Wisconsin State Journal highlights the Waisman Center Autism Treatment Programs, and other options, for children and families with autism. To read the story, please click here.
Carl Ross has been selected to serve as managing director of Waisman Biomanufacturing. His appointment started July 1, following more than a year as its interim director. Located at the University of Wisconsin–Madison Waisman Center, the primary mission of Waisman Biomanufacturing is to help UW scientists and others efficiently translate scientific discoveries into early-stage clinical …
Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation Legend: AT-1 Tg animals display changes in neuronal morphology and imbalanced synaptic plasticity. (A-D) Morphological assessment of hippocampal neurons in culture. Phalloidin staining (upper panels) and unbiased computer-driven reconstruction (lower panels) of both WT and AT-1 Tg neurons (A …
