Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Integrative Single-Cell Transcriptomics Reveal Molecular Networks Defining Neuronal Maturation during Postnatal Neurogenesis Legend: Left: An illustration of coronal section of Nissl-stained adult mouse brain; Confocal images showing that most of DsRed+ (red) cells in DCX-dsRed mouse brains express immature neuron marker doublecortin (DCX, green). Middle: A schematic of the experimental design for single-cell transcriptome analysis. Right: Enrichment …
Alexander disease patient astrocytes have impaired calcium wave propagation Legend: A) Still images over time from mechanical stimulation of 6-month astrocytes loaded with Fluor-4AM and accompanying post-experiment GFAP stains. B) Average duration of increased calcium signal above threshold ± S.D. C) Average proportion of field of view traveled by calcium wave. D) Rate of calcium …
Version 26.0.0.151 of Adobe Flash Player is being rolled out to Waisman PCs today. Ask us or ask Adobe which version you are using.
We present a registration-based semi-automatic mandible segmentation (SAMS) pipeline designed to process a large number of computed tomography studies to segment three dimensional (3D) mandibles.
Waisman Center investigator Luigi Puglielli had trouble with only one class in medical school: biochemistry. Yet today he uses biochemical approaches to study some of the vital molecular mechanisms that regulate brain physiology and pathology across the lifespan. Puglielli, who is a professor in the Department of Medicine, focuses on trying to understand how proteins …
Peripheral nerve regeneration after injury is dependent upon implementation of a novel genetic program in Schwann cells that supports axonal survival and regeneration.
Java Runtime Environment. version 8 update 144 has been released by Oracle which is being installed on Waisman PCs over the next few days. Check with Oracle to see which version of Java you are using.
Our current research is to apply stem cell technology to disease modeling and therapeutic applications for neuromuscular diseases such as ALS (also known as Lou Gehrig’s disease).
When Leila Adamson was born, doctors weren’t sure that she would live for even 63 seconds. More than 63 months later, in July 2017, she will be in Madison, Wisconsin, along with her parents, Kari and James, and her sister, Madelyn, for the 31st annual conference of the Support Organization for Trisomy 18, 13 and …
Investigating the Receptive-Expressive Vocabulary Profile in Children with Idiopathic ASD and Comorbid ASD and Fragile X Syndrome Legend: Association between expressive and receptive vocabulary. Note: This figure illustrates the relationship between expressive and receptive vocabulary for the two groups Citation: Haebig E, Sterling A. (2017) Investigating the Receptive-Expressive Vocabulary Profile in Children with Idiopathic ASD …
