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Pelin Cengiz
Pelin Cengiz, MD – Slide of the Week
TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury
Pelin Cengiz, MD – Slide of the Week
Neonatal hypoxia ischemia (HI) related brain injury is one of the major causes of life-long neurological morbidities that result in learning and memory impairments.
Estrogen receptor alpha mediates protection against hypoxic ischemic brain injury in newborn female mice, study shows
In her practice as a pediatric intensivist, Cengiz noticed that even with similar brain injuries, functional outcomes varied from child to child. “So, I began wondering what could be the potential mechanisms of these differences in outcome”, Cengiz says.
Researcher clinicians help bridge the gap between scientific discovery and medical care – Part 2
There is no one “typical” type of researcher clinician. There are differences in training, percentage of focus on research vs clinic, and type of research done. Many also carry teaching and administrative responsibilities on top of their already demanding positions.
Waisman investigator receives award recognizing her outstanding mentorship of women scientists
Pelin Cengiz, MD, was recently awarded the 2022 Women’s Health Research Mentorship Award by the UW School of Medicine and Public Health (UW SMPH) Group on Women in Medicine and Science (GWIMS) and the Building Interdisciplinary Research Careers in Women’s Health (BIRCWH).
Pelin Cengiz, MD – Slide of the Week
The variability of severity in hypoxia ischemia (HI) induced brain injury among research subjects is a major challenge in developmental brain injury research.
Cengiz receives academic staff excellence awards
Pelin Cengiz, MD, an associate professor in the Department of Pediatrics and a Waisman Center investigator, is among this year’s recipients. She received the Chancellor’s Award for Excellence in Research: Independent Investigator.
Pelin Cengiz, MD
Astrogliosis following hypoxia-ischemia (HI) related brain injury plays a role in increased morbidity and mortality in neonates. Recent clinical studies indicate that the severity of brain injury appears to be sex-dependent and that male neonates are more susceptible to the effects of HI resulting in worse neurological outcomes compared to females with comparable brain injuries.
Pelin Cengiz, MD – Slide of the Week
Title: ERα Signaling Is Required for TrkB-Mediated Hippocampal Neuroprotection in Female Neonatal Mice after Hypoxic Ischemic Encephalopathy Legend: Increases in p-TrkB immuno and protein expressions are sexually differentiated and ERα dependent post-HI. A. Changes in …