Young children with severe traumatic brain injury (TBI) have frequently been excluded from studies due to age and/or mechanism of injury.
Peter Ferrazzano
The 2021 winners: Cool Science Image Contest
Ten images and two videos created by University of Wisconsin–Madison students, faculty and staff have been named winners of the 2021 Cool Science Image Contest.
Peter Ferrazzano, MD – Slide of the Week
Adolescent traumatic brain injury (TBI) is a major public health concern, resulting in over 35,000 hospitalizations in the U.S. each year. While neuroimaging is a primary diagnostic tool in the clinical assessment of TBI, our understanding of how specific neuroimaging findings relate to outcome remains limited. Our study aims to identify imaging biomarkers of long-term neurocognitive outcome after severe adolescent TBI.
Peter Ferrazzano named Weygandt Professor
Waisman investigator, Peter Ferrazzano, MD, has been named the first recipient of the Enid and Jerry Weygandt Professorship in Pediatric Critical Care. Ferrazzano, a Waisman investigator, leads the UW Division of Pediatric Critical Care Medicine which …
Pediatric Brain Care Study (Ferrazzano & Alexander)
The Pediatric Brain Care Study is recruiting typically developing children, 9-17 years old, with no history of head injury for a brain imaging research study. Those who participate will have a MRI brain scanning and …
Peter Ferrazzano, MD – Slide of the Week
Neuroinflammation plays an important role in ischemic brain injury and recovery, however the interplay between brain development and the neuroinflammatory response is poorly understood. We previously described age-dependent differences in the microglial response and the effect of microglial inhibition.
Peter Ferrazzano, MD
Immunostaining and microglia isolation via magnetic cell sorting was performed at postnatal day 2, 9, 30 and 60 (P2, P9, P30, P60). Microglia branching and soma size were quantified using semiautomated software analysis (Imaris, Oxford Insturments).
Treating the trauma of brain injuries
One Wednesday in September, 15-year-old Tristan Thurman went to soccer practice at his high school. The team had just lost a game the day before because the other team had scored goals heading the ball, …
Peter Ferrazzano, MD
Title: Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury. Legend: Figure 1. Minocycline treatment suppresses the microglial response to hypoxia-ischemia (HI) in neonatal and juvenile mice. The number of CD11b+/CD45+ …
Tweaking the immune response shows potential for treating brain injuries
April 15, 2016 Adityarup “Rup” Chakravorty Brain injuries caused by a lack of oxygen and blood flow affect many thousands of children every year, yet “we still don’t have effective treatments for them,” says Waisman …