Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
UW-Madison research published today (Feb. 11, 2019) reveals how one mutation causes fragile X, the most common inherited intellectual disability. “Fragile X syndrome has been studied as a model of intellectual disability because in theory it’s comparatively simple,” says senior author Xinyu Zhao, a professor of neuroscience in the Waisman Center at the University of Wisconsin–Madison.
David Gamm, director of the McPherson Eye Research Institute, and Forward Bio Institute director Bill Murphy explain how stem cell scientists at UW–Madison are working with industry to put scientific breakthroughs on the path to helping patients.
It’s not a cure for Down syndrome that Dave Witte and Cristina Delgadillo want for their 5-year-old daughter. “Olivia is our daughter and we love her, and we love her because of who she is. And part of who she is, is she has Down syndrome,” Witte says. But they would be happy if stem …
Winning a game of darts requires being accurate. A player who can pick a spot on the board, focus their mind, and execute the specific motor action needed to land the bullseye will win the game. And if they miss, well, practice makes perfect.
One of the goals of the study is to discover how genetic variations in young people with ASD are related to brain changes that lead to clinical symptoms of the disorder, such as impaired social interaction and repetitive behaviors. “If you think about it, in between genes and clinical symptoms [of ASD] are changes in brain development,” says Lainhart. “Genes first impact brain development, and as a result of changes in how the brain develops, there are clinical manifestations of what we recognize as ASD.”
We’re delighted to share a video highlighting many of the strides we have made over the past year. Your generous and thoughtful contributions help us continue to pioneer research and expand clinical services that benefit individuals and families impacted by developmental disabilities and neurodegenerative diseases. Together we are transforming lives and building brighter futures—without you, …
We know enough about methylphenidate – more commonly known as Ritalin – to prescribe it to mediate attention challenges. However, UW researchers aided by Waisman scientists are taking the first steps toward a deeper understanding of how the drug impacts the brain. Ritalin causes greater functional connectivity between the caudate, a multi-functional deep brain structure, …
Black youths are overrepresented in the criminal justice system. Yet, says University of Wisconsin–Madison Psychology Professor James Li, they are underrepresented by research studies examining the behaviors that can lead them there, and the potential interventions to help prevent it. Most studies have focused on predominantly white adolescents.
The Waisman Center hosted their annual poster fair on Thursday, Dec. 6. The well-attended event featured nearly fifty posters highlighting the interdisciplinary research of students, graduates and investigators working at the Waisman Center. This event gives researchers an opportunity to showcase what they have been working on and mingle over their findings with the public …
Su-Chun Zhang, a Waisman Center investigator, was the first person in the world to craft human brain cells both from human embryonic stem (ES) cells and later from induced pluripotent (iPS) cells. In a recent interview with UW–Madison, Zhang answers questions on his career in stem cell neuroscience and the challenges that stem cell research may …
