Mancheski Foundation funds next-gen research on Down syndrome and Alzheimer’s

A gift from the Mancheski Foundation continues to provide integral support to doctoral student Matthew Zammit as he furthers his research on the progression of Alzheimer’s disease in individuals with Down syndrome. Zammit is beginning …

Clinical trial for Ebola vaccine developed at UW–Madison underway in Japan

As of this week, a phase one clinical trial to test a potential new Ebola vaccine developed by researchers at the University of Wisconsin–Madison is underway in Japan. Fifteen healthy young men* will receive two doses of the experimental vaccine. If the first group tolerates the vaccine, an additional group of up to 20 volunteers will receive a higher dose of the vaccine.

Doug Dean, III, PhD – Slide of the Week

White matter microstructure, essential for efficient and coordinated transmission of neural communications, undergoes pronounced development during the first years of life, while deviations to this neurodevelopmental trajectory likely result in alterations of brain connectivity relevant to behavior. Hence, systematic evaluation of white matter microstructure in the normative brain is critical for a neuroscientific approach to both typical and atypical early behavioral development.

UW-Madison brain scan studies seek to pinpoint signs of Alzheimer’s

Waisman Center investigator Brad Christian and Waisman Center affiliates Sterling Johnson and Barbara Bendlin were featured in a Nov. 26 Wisconsin State
Journal article this week about Alzheimer’s research. The article is a part of a series on Alzheimer’s called “Fading away: Wisconsin’s dementia crisis,” which chronicles the doubling rate of dementia patients in Wisconsin.

Karla Ausderau, PhD – Slide of the Week

Mealtime is an important family routine commonly affected for families with children with autism spectrum disorders (ASD). Limited research is available regarding strategies families incorporate to support mealtime engagement. The purpose of this study was to explore the frequency and characterize the purpose of Props used during mealtimes with children with ASD.

Richard J Davidson, PhD – Slide of the Week

Reduced hippocampal volume is frequently observed in posttraumatic stress disorder (PTSD), but the psychological processes associated with these alterations remain unclear. Given hippocampal involvement in memory and contextual representations of threat, we investigated relationships between retrospectively reported combat exposure, perceived threat, and hippocampal volume in trauma-exposed veterans.

Christopher L. Coe, PhD – Slide of the Week

Maternal recall of distress and health concerns during pregnancy correlated with cord blood ZnPP/H indices (r = 0.21, P < .01), even in the absence of major traumatic events. When concurrent with other known risks for iron deficiency, including maternal adiposity, socioeconomic status, and race, maternal stress had a summative effect, lowering cord blood iron.