University of Wisconsin–Madison

Tag: Sigan Hartley

Changes in walking patterns could be an important new screening tool for Alzheimer’s in individuals with Down syndrome

Individuals with Down syndrome have a 90% lifetime risk of developing Alzheimer’s disease.

METabolic Health, Lifestyle, and Risk of Co-Occurring Health Conditions in Down Syndrome (MET-DS) – (Hartley)

The METabolic Health, Lifestyle, and Risk of Co-Occurring Health Conditions in Down Syndrome (MET-DS) study is part of the NIH INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndrome) and its Collaboration for Down Syndrome Progress (CDP) Program—national initiatives working to improve the health and quality of life of people with …

A family’s commitment to Down syndrome research at the Waisman Center spans four decades and counting

When Heather Huismann was in middle school she called the police on her teacher. “He was not teaching me very well,” Heather says.

Advising research through the lens of lived experience: How individuals with disabilities and their families are shaping research

NOTE: Each individual interviewed for this story stated their preference between person-first or identity-first language. The language used reflects the preference of each person. Researchers interviewed use identity-first language in alignment with the preferences of many of those in the autistic community. Who is considered an expert in autism? Or cerebral palsy? Or Down syndrome? …

Sigan Hartley, research team receive $9 million National Institutes of Health grant to study Down syndrome

Sigan Hartley, 100 Women Distinguished Chair in Human Ecology and Human Development & Family Studies professor, and a team of researchers have received a $9 million grant from the National Institutes of Health (NIH).

Sigan Hartley, PhD – Slide of the Week

AT(N) biomarker profiles and Alzheimer’s disease in People with Down syndrome

Neurodegeneration research at the Waisman Center from gene to organelle to cell to brain

Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease, and retinitis pigmentosa all have different manifestations and affect different body functions, but they are all connected by one mechanism: neurodegeneration.

Understanding the connection between Down syndrome and Alzheimer’s disease

Allison and Amber Westemeier get excited every time they take a trip to the Waisman Center from Oshkosh, WI.

The beginnings and evolution of brain imaging at the Waisman Center

The development of brain imaging techniques has helped us understand emotion, intellectual and developmental disabilities, and neurodegenerative diseases in ways we could not before.

Weight loss may be early predictor of Alzheimer’s disease in Down syndrome

Unintentional weight loss in people with Down syndrome may predict the onset of Alzheimer’s disease long before typical cognitive symptoms like memory loss and dementia are apparent.