Unintentional weight loss in people with Down syndrome may predict the onset of Alzheimer’s disease long before typical cognitive symptoms like memory loss and dementia are apparent.
Sigan Hartley
Waisman postdoctoral training program: Training the next generation of IDD researchers
The first two years of the grant provided funding for two seminars in an academic year, but in a short span, seeing the tangible benefits these had, they expanded from two lectures a year, to two a month.
Thoughts of gratitude: The Dewey family is a catalyst of support for the Waisman Center
Individuals with Down syndrome are at higher risk of developing Alzheimer’s disease, and it typically presents it at an earlier age than the general population. It is estimated that 90% of people with Down syndrome will have developed Alzheimer’s by age 65.
Sigan Hartley, PhD – Slide of the Week
People with Down Syndrome (DS) are at high risk for Alzheimer’s disease (AD) because of their unique biology and provide an unparalleled opportunity to develop biomarkers of preclinical AD.
Postdoctoral program equips a new generation of scientists in IDD research
For more than 26 years, the center’s Postdoctoral Training Program in Intellectual and Developmental Disabilities Research has helped shape the careers and research paths of 53 postdoctoral researchers through multidisciplinary training in social, epidemiological, behavioral and biobehavioral research on intellectual and developmental disabilities (IDD).
Sigan Hartley, PhD – Slide of the Week
Boxplots depicting median and variation for episodic memory score by PET amyloid beta (Aβ–vs. Aβ+) and tau (TLvs. TH) status in Braakregions I to VI.
Studying the connection between Alzheimer’s and Down syndrome for Down syndrome awareness month
By Emily Leclerc, Waisman Science Writer The month of October is Down Syndrome Awareness Month and is dedicated to not only raising awareness about Down syndrome but also to celebrating the abilities and accomplishments of …
Sigan Hartley, PhD – Slide of the Week
There is a critical need to identify measures of cognitive functioning sensitive to early Alzheimer’s disease (AD) pathophysiology in Down syndrome to advance clinical trial research in this at-risk population. The objective of the study was to longitudinally track performance on cognitive measures in relation to neocortical and striatal amyloid beta (Aβ) in non-demented Down syndrome.
New NIH-funded initiative will examine Alzheimer’s disease in people with Down syndrome
A team of researchers at the University of Wisconsin–Madison is part of a new multi-institution effort to better understand Alzheimer’s disease in adults with Down syndrome. Adults with Down syndrome are at high risk for …
Sigan Hartley, PhD – Slide of the Week
Family research in the field of ASD has focused on describing the impact of child challenges on parents, usually mothers, and given little attention to the ways in which mothers and fathers reciprocally influence the development of the child with ASD.