Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
A newly funded project will combine the expertise of four Waisman Center investigators to develop advanced machine learning methods for studying brain organoids, three-dimensional cell clusters grown from stem cells that closely mimic key aspects of human brain development.
A new machine learning algorithm developed at UW-Madison is helping researchers untangle a complex puzzle: the molecular mechanisms behind developmental disabilities and neurodegenerative diseases. COSIME, created by the lab of Waisman investigator Daifeng Wang, PhD, associate professor of biostatistics and medical informatics, and computer sciences, offers a powerful new way to integrate and interpret multiple types of biological data which can give scientists a clearer view of how different cellular clues come together to shape disease outcomes.
Building a complete developmental trajectory of cells is close to impossible with today’s technology, but new technology developed at the Waisman Center is taking scientists a step closer to achieving it. Machine learning, a form of artificial intelligence, can step in to help fill in the gaps.
A new app developed at the Waisman Center makes it easier than ever for researchers to use machine learning techniques to analyze large complex data sets without specialized or specific training.
A new study from researchers at the Waisman Center and The Ohio State University will investigate aging in autistic adults.
Like a game of Wheel of Fortune, where you have to fill in missing letters to guess the hidden phrase, analyzing data sometimes requires estimating missing data points by relying on available information in order to get the full picture of what’s being studied.
Today, many researchers are using brain organoids – miniaturized and simplified versions of organs produced in a dish typically from stem cells – as analogs for studying the development of the human brain.
For something so small, neurons can be quite complex — not only because there are billions of them in a brain, but because their function can be influenced by many factors, like their shape and genetic makeup.
An analysis of electronic health records for 1.7 million Wisconsin patients revealed a variety of health problems newly associated with fragile X syndrome.
Recent advances in genome sciences — the study of an organism’s complete set of DNA — present a golden opportunity to identify the genetic causes and underlying mechanisms of intellectual and developmental disabilities. These discoveries will also improve diagnosis and potential treatments for these conditions. To advance science in this innovative field, the Waisman Center …
