Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
An analysis of electronic health records for 1.7 million Wisconsin patients revealed a variety of health problems newly associated with fragile X syndrome.
Waisman researcher Ellen Peng, PhD, is the recipient of an Editor Award from the American Speech-Language Hearing Association (ASHA) for her work on the impact of room acoustics on listener comprehension. Her article “Listening Effort by Native and Nonnative Listeners Due to Noise, Reverberation, and Talker Foreign Accent During English Speech Perception,” which is based …
Alexander disease (AxD) is a rare neurodegenerative disorder that is caused by dominant mutations in the gene encoding glial fibrillary acidic protein (GFAP), an intermediate filament that is primarily expressed by astrocytes. In AxD, mutant GFAP in combination with increased GFAP expression result in astrocyte dysfunction and the accumulation of Rosenthal fibers.
Twins Sebastian and Charlotte Sundly are quite the contrasting pair, yet they balance one another out perfectly in some interesting and unexpected ways.
Polymeric scaffolds are revolutionizing therapeutics for blinding disorders affecting the outer retina, a region anatomically and functionally defined by light-sensitive photoreceptors. Recent engineering advances have produced planar scaffolds optimized for retinal pigment epithelium monolayer delivery, which are being tested in early stage clinical trials.
A new study from the Binaural Hearing and Speech (BHS) Lab at the Waisman Center examines functional near-infrared spectroscopy (fNIRS) – a neuroimaging option that is safe for individuals with metal implants
To slow the progression of COVID-19, the Centers for Disease Control (CDC) and the World Health Organization (WHO) have recommended wearing face coverings. However, very little is known about how occluding parts of the face might impact the emotion inferences that children make during social interactions.
The adaptability of children with disabilities has inspired Bernadette Gillick, PhD, MSPT, PT for the majority of her career.
Mice carrying the GABAA receptor β3(N265M) point mutation, which renders receptors incorporating β3-subunits insensitive to many general anesthetics, have been used experimentally to link modulation of different receptor subtypes to distinct behavioral endpoints. Remarkably, however, the effect of the mutation on the susceptibility to modulation by isoflurane (a standard reference agent for inhalational vapors) has never been tested directly. Therefore, we compared the modulation by isoflurane of expressed α5β3(N265M)γ2L receptors with their wild type counterparts.
Grafting neurons grown from monkeys’ own cells into their brains relieved the debilitating movement and depression symptoms associated with Parkinson’s disease, researchers at the University of Wisconsin–Madison reported today.
