Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
A recent study shows that people at low genetic risk for attention deficit hyperactivity disorder (ADHD) are not only less likely to have the disorder, they also have better than expected economic, health and behavioral outcomes in later life.
As of this week, a phase one clinical trial to test a potential new Ebola vaccine developed by researchers at the University of Wisconsin–Madison is underway in Japan. Fifteen healthy young men* will receive two doses of the experimental vaccine. If the first group tolerates the vaccine, an additional group of up to 20 volunteers will receive a higher dose of the vaccine.
White matter microstructure, essential for efficient and coordinated transmission of neural communications, undergoes pronounced development during the first years of life, while deviations to this neurodevelopmental trajectory likely result in alterations of brain connectivity relevant to behavior. Hence, systematic evaluation of white matter microstructure in the normative brain is critical for a neuroscientific approach to both typical and atypical early behavioral development.
Waisman Center investigator Brad Christian and Waisman Center affiliates Sterling Johnson and Barbara Bendlin were featured in a Nov. 26 Wisconsin State Journal article this week about Alzheimer’s research. The article is a part of a series on Alzheimer’s called “Fading away: Wisconsin’s dementia crisis,” which chronicles the doubling rate of dementia patients in Wisconsin.
Mealtime is an important family routine commonly affected for families with children with autism spectrum disorders (ASD). Limited research is available regarding strategies families incorporate to support mealtime engagement. The purpose of this study was to explore the frequency and characterize the purpose of Props used during mealtimes with children with ASD.
Reduced hippocampal volume is frequently observed in posttraumatic stress disorder (PTSD), but the psychological processes associated with these alterations remain unclear. Given hippocampal involvement in memory and contextual representations of threat, we investigated relationships between retrospectively reported combat exposure, perceived threat, and hippocampal volume in trauma-exposed veterans.
Maternal recall of distress and health concerns during pregnancy correlated with cord blood ZnPP/H indices (r = 0.21, P < .01), even in the absence of major traumatic events. When concurrent with other known risks for iron deficiency, including maternal adiposity, socioeconomic status, and race, maternal stress had a summative effect, lowering cord blood iron.
Undergraduates at the University of Wisconsin–Madison are taking less time to complete their degrees, setting a record on a key measure of student success. The average time-to-degree for 2018-19 bachelor’s degree recipients was 3.96 elapsed calendar years, the lowest since the university began actively tracking the measure in the 1980s and the first time the number has dropped below four years, according to the university’s Office of Academic Planning and Institutional Research.
We have seen a profound increase in lifespan for individuals with Down syndrome (DS) in the past few decades leading to a large and somewhat understudied population of middle- and older aged adults with DS. One health condition consistently seen in clinic-based DS samples is dementia (including Alzheimer’s disease).
Not so many years ago, people with Down syndrome rarely survived to middle age. Many died young due to heart problems associated with the congenital condition. Today, advances in treatment have allowed them to live longer, healthier lives.
