Several Waisman Center investigators played key roles in crafting research proposals that were recently selected as ‘cluster hires’ by the University of Wisconsin-Madison. UW–Madison’s Cluster Hiring Initiative was launched in 1998 as an innovative partnership …
Luigi Puglielli
Luigi Puglielli, MD, PhD
Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation Legend: AT-1 Tg animals display changes in neuronal morphology and imbalanced synaptic plasticity. (A-D) Morphological assessment of hippocampal neurons …
The chatter within our cells
Waisman Center investigator Luigi Puglielli had trouble with only one class in medical school: biochemistry. Yet today he uses biochemical approaches to study some of the vital molecular mechanisms that regulate brain physiology and pathology …
Novel mouse model sheds new light on autism spectrum disorder
A new mouse model, developed by researchers at the University of Wisconsin–Madison, is the first to show that when more of a specific biological molecule moves between different parts of nerve cells in the mouse brain, it can lead to behaviors that resembles some aspects of autism spectrum disorder (ASD) in humans.
UW researchers find possible treatment for Alzheimer’s
January 19, 2016 Channel 3000 University of Wisconsin researchers say they’ve found a treatment to clean up the plaques that form in the brain of mice with Alzheimer’s disease. The research published in the journal …