Title: Increasing Nrf2 activity in astrocytes confers protection to Nrf2 knockout neurons Legend: Nrf2 KO cultures were traduced with 50 MOI adenovirus-Nrf2-GFP or adenovirus-GFP 48 hours prior to H2O2 treatment. Cultures were immunohistochemically analyzed following treatment with 50 µM …
Slide of the Week
Ed Hubbard, PhD
Title: Perceptual Ratio Processing Predicts Fractions Skills Legend: (Lay): College students were asked to decide which of two ratios were larger (examples in a-d) that were presented for 1.5 seconds. We show that people who …
Derek Hei, PhD
Title: iPSC derived Optic Vesicles (OVs)/Neural Retinal Progenitors (NRPs) – Production, Characterization and Cryopreservation Legend: 1) Representative pictures of selected OVs derived from iPSCs grown on E8/Matrigel. iPSCs, cultured on E8/Matrigel, mTeSR1/Matrigel, and E8/vitronectin, were …
Sigan Hartley, PhD
Title: Support Needs of Fathers and Mothers of Children and Adolescents with Autism Spectrum Disorder Legend: Left, top image: The most support needs most frequently rated as both important and unmet for both mothers and …
Samuel P Gubbels, MD
Title: Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreER(T2)/tdTomato-reporter mice Legend: Left image: Cochlea from an adult nestin-CreERT2/tdTomato-reporter mouse 56 days post tamoxifen injection. Low power macroscopic imaging …
Timothy M. Gomez, PhD
Legend: Top: A-B. 3D rendering of structured illumination microscopy (SIM) images of a human forebrain neuron growth cone triple-labeled for F-actin (red), ßIII tubulin (blue) and ADAM17 (green). A view of the apical surface (A) shows …
H. Hill Goldsmith, PhD
Legend: Left image: Children chronically at-risk for sensory processing disorders are more likely to have lower birthweight, lower gestational age, less sootheable and more fearful temperaments as toddlers. Right image: Severity of Age 4 sensory related …
David Gamm, MD, PhD
Title: Pharmacological modulation of photoreceptor outer segment degradation in Best disease patient-derived hiPSC-RPE Legend: (a) Representative western blot analysis comparing the amount of the POS protein RHO in untreated and VPA-treated (500 µmol/l) BD hiPSC-RPE at …
Peter Ferrazzano, MD
Title: Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury. Legend: P9 and P30 mice were exposed to unilateral hypoxia-ischemia and treated with minocycline or vehicle. A, B. Double immunohistological staining …
Susan Ellis Weismer, PhD
Legend: Latent growth curve modeling of longitudinal data (age 2-5 years) for 129 young children with ASD revealed four severity trajectory classes based on calibrated severity scores from the Autism Diagnostic Observation Schedule (ADOS): Persistent …