Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Title: Four-year-olds’ selective production of verbal cues predicts their spatial skills Legend: (Top panel) Sample trials of spatial tasks children completed (A) mental transformations, (B) spatial analogies, (C) feature binding, and (D) picture rotation. (Bottom left panel) Examples of the spatial scene description task trial types, in which children could use (A) three cues, color, …
Title: Young children’s automatic encoding of social categories Legend: Mean encoding scores at each age in each condition. One-sample t-tests comparing performance to chance (0) appear above each bar in the graph. Error bars depict standard error. Children encoded gender as early as four years of age, but no age group showed significant encoding of …
Legend: Results of a study in which toddlers learned new words in environments with different levels of background noise. The solid vertical line marks the onset of the target word. The dashed vertical line marks the beginning of the test window (300 ms after the onset of the spoken word). Chance performance is .5. Toddlers …
Legend: The major foci in the brain that appear to show disparities in poor children are the hippocampus and frontal lobe. These 3D renderings depict the hippocampus in blue and the frontal lobe in red/yellow. Citation: Hair, N. L., Hanson, J. L., Wolfe, B. L., & Pollak, S. D. (2015). Association of child poverty, brain …
Legend: Change in HTKS total score by treatment group. Age of child controlled in analyses. DR dialogic reading only (TAU), MI mindfulness intervention Citation: Poehlmann-Tynan J, Vigna AB, Weymouth LA, Gerstein ED, Burnson C, Zabransky M, Lee P, Zahn-Waxler C. (2015) A Pilot Study of Contemplative Practices with Economically Disadvantaged Preschoolers: Children’s Empathic and Self-Regulatory …
TDP-43 mislocalization in a mouse model of Alexander disease Legend: Mislocalized TDP-43 colocalizes with GFAP in GfapR236H/+ mice. TDP-43 (red) and GFAP (green) immunolabeling in coronal brain sections from 10-week-old mice. Nuclei are labeled with DAPI (blue). In WT mice, TDP-43 is primarily localized to neuronal nuclei (pyramidal layer of the hippocampus shown here), with very little colocalization with GFAP. In GfapR236H/+mice, TDP-43 …
Title: Parents as a Team: Mother, Father, a Child with Autism Spectrum Disorder, and a Spinning Toy Citation: Douglas W. Maynard, T A McDonald, Trini Stickle. (2015) Parents as a Team: Mother, Father, a Child with Autism Spectrum Disorder, and a Spinning Toy. Journal of Autism and Developmental Disorders. Abstract: This paper is a single …
Legend: Fig. 1. Frequency of specific CGG repeat lengths >40 for men and women. Citation: Maenner MJ, Baker MW, Broman KW, Tian J, Barnes JK, Atkins A, McPherson E, Hong J, Brilliant MH, Mailick MR. (2013). FMR1 CGG expansions: prevalence and sex ratios. American Journal of MedicalGenetics Part B: Neuropsychiatric Genetics. 162B(5):466-73. Abstract: We have estimated …
Title: Listening effort, also known as cognitive load, is measured with pupil dilation (pupillometry). When speech sounds are degraded, people expend greater amount of ‘cognitive load’ to decipher the meaning of the speech. Legend: A: Subjects listen to sentences while their pupil size is measured using an eye tracker. Stimuli are varied from highly natural …
Title: Item Response Theory Analysis of ADHD Symptoms in Children with and without ADHD Legend: The “continuum” of ADHD in children. The IRT analysis shows that there is minimal clinical difference (i.e., within 1 standard deviation of the mean) on the general ADHD factor between a child who scores a 9 and a child who …
