Legend: Left panel: General patterns of [11C]PiB binding in participants with Down syndrome (DS). PiB binds to amyloid-β plaques, a neuropathological hallmark of Alzheimer’s disease (AD). The top row shows nonspecific white matter binding. The …
Slide of the Week
Qiang Chang, PhD
Title: Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis Legend: Representative images (left) of adult neural progenitor cells (aNPCs) isolated from wild type (WT) and Mecp2S421A;S424A/y hippocampus with BrdU pulse labeling, followed by immunocytochemistry analysis. (middle) Representative …
Pelin Cengiz, MD
Title: Up-regulation of NHE1 protein expression in reactive hippocampal astrocytes Legend: A.Expression of NHE1 protein in hippocampal astrocytes. Immunofluorescence signals of NHE1 and GFAP were shown under normoxia control or OGD (2 h) plus 0 …
Anita Bhattacharyya, PhD
Title: iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth Legend: Left panel: Skin cells from individuals with fragile X syndrome (FXS) can be reprogrammed into induced pluripotent stem cells (iPSCs) that …
Mei Baker, MD
Title: Sequencing Library Generation Legend: Each probe contains two parts of sequences: one for targeting interested CFTR gene regions, and another for annealing to PCR primers. The DNA templates containing targeted CFTR regions were generated by a …
Karla Ausderau, PhD
Title: Sensory subtypes in children with autism using a latent profile transition analysis Legend: Four clinically distinct and homogeneous sensory subtypes were found to characterize children with autism spectrum disorder (ASD) in a large longitudinal …
Anjon Audhya, PhD
Titel: Imaging of TFG, a protein implicated in neurodegenerative disease, across a variety of scales Legend: Staining of TFG (green) and a marker of the endoplasmic reticulum (red) in human epithelial cells (left). The localization …
Jennifer Asmus, PhD
Title: Classroom observations of social interactions between high school students with significant disabilities and their general education peers Legend: The average rate (number) of interactions per hour for focus students with significant disabilities with any general …
Andrew Alexander, PhD
Title: Multiple contrast MRI with retrospective motion correction Legend: Representative example of multiple image contrasts from a new brain imaging technique MPnRAGE developed in the Alexander Lab in the Waisman Brain Imaging Core. The MPnRAGE …