Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Voice pitch is an essential feature for speech understanding. Envelope following responses (EFRs) are a useful EEG measure to infer the encoding of voice pitch and can be elicited by band-limited speech to assess the processing of voice pitch in a frequency-specific manner.
Waisman Center researchers are creating a new approach to study how changes to brain development in the womb result in intellectual disability in people with Down syndrome.
Women with intellectual and developmental disabilities (IDD) face increased risk of adverse maternal pregnancy outcomes, yet less is known about infant outcomes.
The University of Wisconsin-Madison will be one of 25 sites to study early brain and behavior development and the impact of early exposure to substances – such as opioids – and social stressors in infants and young children.
Although research demonstrates that autistic children are at risk of poor sleep quality, very little is known about sleep quality and its impact on quality of life in autistic adults.
Ten images and two videos created by University of Wisconsin–Madison students, faculty and staff have been named winners of the 2021 Cool Science Image Contest.
Maternal and environmental factors influence brain networks and architecture via both physiological pathways and epigenetic modifications.
The purpose of the present study was to investigate the hypothesis that women with autism have poorer health compared with men with autism, and compared with women without autism.
The uncinate fasciculus is a white matter tract that may facilitate emotion regulation by carrying connections from the prefrontal cortex to regions of the temporal lobe, including the amygdala. Depression and anxiety are associated with reduced uncinate fasciculus fractional anisotropy (FA) – a diffusion tensor imaging measure related to white matter integrity.
Adults with Down syndrome (DS) are predisposed to Alzheimer’s disease (AD) and reveal early amyloid beta (Aβ) pathology in the brain. Positron emission tomography (PET) provides an in vivo measure of Aβ throughout the AD continuum. Due to the high prevalence of AD in DS, there is need for longitudinal imaging studies of Aβ to better characterize the natural history of Aβ accumulation, which will aid in the staging of this population for clinical trials aimed at AD treatment and prevention.
