Category: Research

Moving forward in the search for genetic clues to understand autism

There’s a saying in the autism community: If you have met one person with autism, you have met one person with autism. That’s because “as the name implies, autism spectrum disorder (ASD) exists on a spectrum with a wide range of symptoms, skills and levels of severity with which it impacts a person’s daily life,” …

Ebola vaccine inches toward human clinical trials

A whole-virus vaccine to confront Ebola, the rare but often fatal hemorrhagic disease that periodically erupts in sub-Saharan Africa, may soon be one step closer to the clinic. With the help of experts at Waisman Biomanufacturing, within the University of Wisconsin–Madison’s Waisman Center, UW–Madison School of Veterinary Medicine Professor Yoshihiro Kawaoka will lead a $3 …

NBC15 highlights Rett syndrome and Waisman Center research

NBC15’s Morning Show and reporter Kalie Greenberg shared a story about Laurel Cooper, a 9-year-old girl who has Rett syndrome, and her family. Rett syndrome is a rare, non-inherited neurological disorder that mostly affects girls and causes severe deterioration in their ability to speak, eat, move and even breathe easily. Rett syndrome has no cure. …

Progress made toward treatment for rare, fatal neurological disease

After more than a decade of work, researchers at the University of Wisconsin–Madison’s Waisman Center reported promising results in the lab and in animal models that could set the stage for developing a treatment for Alexander disease, a rare and usually fatal neurological disease with no known cure.

Childhood stress and life risks

Adults who lived high-stress childhoods have trouble reading the signs that a loss or punishment is looming, leaving themselves in situations that risk avoidable health and financial problems and legal trouble.

Mining the cerebellum for its role in speech

“We found that the folks with cerebellar damage responded to these unpredictable changes to a larger extent than those without any damage,” says Parrell. “It was totally unexpected.”

New faculty focus: Lauren Bishop-Fitzpatrick

A Q&A with new Waisman Center investigator Lauren Bishop-Fitzpatrick. How did you get into your field of research? Like many people who pursue social work degrees, I always knew that I wanted to spend my career helping others. Although I first volunteered with children with autism when I was 15, it was not until I took …

The chatter within our cells

Waisman Center investigator Luigi Puglielli had trouble with only one class in medical school: biochemistry. Yet today he uses biochemical approaches to study some of the vital molecular mechanisms that regulate brain physiology and pathology across the lifespan. Puglielli, who is a professor in the Department of Medicine, focuses on trying to understand how proteins …

Madison County girl hopes to help unlock cure of rare disease

  Waisman Center Director, Albee Messing, is collaborating with researchers at the Children’s Hospital of Philadelphia to better understand the progression of Alexander disease, a rare and fatal neurological disorder with no known cure. In a news story in the Belleville News-Democrat, Messing said that the study has already led scientists to several breakthroughs in …

Know Your Madisonian: Albee Messing focuses on Alexander disease

Waisman Center Director, Albee Messing, VMD, PhD, was recently featured in the Know Your Madisonian column by David Wahlberg in the Wisconsin State Journal. To read the full interview, please click here. David Wahlberg, Wisconsin State Journal