Proposals by Waisman investigators selected for UW-Madison Cluster Hire Initiative

Several Waisman Center investigators played key roles in crafting research proposals that were recently selected as ‘cluster hires’ by the University of Wisconsin-Madison. UW–Madison’s Cluster Hiring Initiative was launched in 1998 as an innovative partnership …

Waisman research into rare syndrome offers hope for families

Laurel Cooper is 8 years old and full of sass and spunk. She finds it hilarious when her older sister, Annalise, gets into trouble. She loves music, and being in the thick of things. Cooper also has Rett syndrome, a rare, non-inherited neurological disorder that mostly affects girls and causes severe deterioration in their ability to speak, eat, move and even breathe easily. Rett syndrome has no cure.

Qiang Chang, PhD

Title: Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis Legend: Representative images (left) of adult neural progenitor cells (aNPCs) isolated from wild type (WT) and Mecp2S421A;S424A/y hippocampus with BrdU pulse labeling, followed by immunocytochemistry analysis. (middle) Representative …

Waisman scientists model human disease in stem cells

Many scientists use animals to model human diseases. Mice can be obese or display symptoms of Parkinson’s disease. Rats get Alzheimer’s and diabetes. But animal models are seldom perfect, and so scientists are looking at a relatively new type of stem cell, called the induced pluripotent stem cell (iPS cell), that can be grown into specialized cells that become useful models for human disease.