We need to know STAT: Mechanisms behind GFAP accumulation in Alexander disease involve transcription factor STAT3.

The hallmarks of Alexander disease, aggregation of misfolded GFAP proteins and dysregulation of brain cells called astrocytes, may be stopped and reversed in rodent models with the inactivation of the transcription factor STAT3.

Building bridges between disciplines: Marsha Mailick’s interdisciplinary research and leadership at the Waisman Center

Multiple angles of vision all focused on a common question is what attracted Marsha Mailick, PhD, emeritus vice chancellor for research and graduate education at the University of Wisconsin-Madison, to the Waisman Center more than 35 years ago.