Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Fragile X messenger ribonucleoprotein 1 protein (FMRP) deficiency leads to fragile X syndrome (FXS), an autism spectrum disorder.
To the naked eye, they look like tiny blobs free floating in a pink liquid. Under a light microscope, they look similar. But organoids, a 3-D mini version of an organ grown in a lab, may contain invaluable information about how the human brain develops.
DNA libraries generated from 235 post mortem human brain samples were sequenced using 150 bp, paired end Illumina chemistry to a desired depth of 30X coverage. Reads were aligned to either the linear GRCh38 alt-free reference genome, the linear telomere to telomere hs1 reference genome, or the draft human pangenome.
Feeding challenges seen in an autistic child’s first few years can help predict the type and severity of feeding challenges the child may experience later on.
Genotypes are strongly associated with disease phenotypes, particularly in brain disorders. However, the molecular and cellular mechanisms behind this association remain elusive.
We want to better understand how autistic children with and without attention-deficit/hyperactivity disorder (ADHD) differed in their motor skills, sensory features, and daily living skills.
The Children’s Resource Center-South (CRC) named Meredith Vitaioli as their new director in April.
The most common cause of genetic neuropathy, classified as Charcot-Marie-Tooth disease, is a 1.4 Mb duplication of the PMP22 gene.
The nominations for this year’s recipients read like a textbook of great mentoring practices – meeting students where they’re at, getting to know them as scholars and individuals, and guiding their learning with just the right mix of challenge and support.
The myotendinous junction (MTJ) is an integrated structure that transduces force across the muscle-tendon boundary, making the region vulnerable to strain injury.
