Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Cytosolic citrate is imported from the mitochondria by SLC25A1, and from the extracellular milieu by SLC13A5. In the cytosol, citrate is used by ACLY to generate acetyl-CoA, which can then be exported to the endoplasmic reticulum (ER) by SLC33A1.
Autism is often associated with complex tasks like social processing and language and the later-developing brain regions that control them. But what if autism is more rooted in the earliest developing and most reflex-like part of the brain – the brainstem?
Adolescents who experience sustained childhood maltreatment show high, inflexible cortisol levels that persist throughout the day in different social contexts, a new study shows. This flattened cortisol rhythm may be a pathway for poorer physical and mental health in youth that experience abuse.
[uw-reusable-content id=’29795′] Down syndrome is a genetic condition in which all cells in a person’s body have an extra copy of chromosome 21, also known as trisomy 21. Having this extra chromosome affects how an individual’s body and brain develops. Approximately one in 772 babies in the United States are born with Down syndrome, according …
[uw-reusable-content id=’29795′] Natasha Méndez Albelo, graduate student in the lab of Waisman investigator Xinyu Zhao, PhD, was awarded the competitive SCRMC Graduate Training Award from the UW–Madison Stem Cell and Regenerative Medicine Center. This award recognizes and provides support and unique training opportunities to promising graduate students doing research in stem cell and regenerative medicine. …
The purpose of this research is to better understand how skills related to executive function like memory and flexible thinking are related to grammar and language comprehension and production in children with FXS, DS, and DLD, and a comparison group of neurotypical children.
Title: Importance of Predictability for Children Citation: Xu, Y., Harms, M. B., Green, C. S., Wilson, R. C., & Pollak, S. D. (2023). Childhood unpredictability and the development of exploration. Proceedings of the National Academy of Sciences of the United States of America, 120(49), e2303869120. https://doi.org/10.1073/pnas.2303869120 Abstract: Early in development, the process of exploration helps children gather …
It is well established that brain development looks different for individuals with Down syndrome, but how early do these differences appear?
Our Goals: We hope you will be a part of the first study for young adults with Down syndrome to combine: Who can help? Young adults with Down syndrome who are: How much time will I need to be there? We would like you and your Caregiver to come for 2-3 days so we will …
Intelligibility as a function of speaking rate and age in different utterance lengths
