Seth Pollak: A career dedicated to understanding child emotion

The fun decals on the colorful walls and the cheerful environment gives it away, the third floor of the Waisman Center is dedicated to children. This space is where Seth Pollak, PhD, has spent most of his career studying child emotion, and how early life experiences shape the brain during development.

New machine learning algorithm improves estimation and integration of single-cell data

Like a game of Wheel of Fortune, where you have to fill in missing letters to guess the hidden phrase, analyzing data sometimes requires estimating missing data points by relying on available information in order to get the full picture of what’s being studied.

We need to know STAT: Mechanisms behind GFAP accumulation in Alexander disease involve transcription factor STAT3.

The hallmarks of Alexander disease, aggregation of misfolded GFAP proteins and dysregulation of brain cells called astrocytes, may be stopped and reversed in rodent models with the inactivation of the transcription factor STAT3.

Understanding autism from the minute to the masses: Autism research at the Waisman Center

Autism spectrum disorder (ASD) is an intricate and complicated diagnosis. The spectrum of presentations and severity is as expansive as the theorized causes. Autism’s complexity and breadth of impacts on a person’s life means that it has a multitude of facets to investigate.