Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Mean physical and behavioral depressive symptoms on the Reiss Screen of Maladaptive Behavior (RSMB) across four data collection cycles in sample of 262 adults with Down syndrome. Blue line is for those with low PET amyloid and green line for those with elevated PET amyloid.
Autistic adults may face changes in their autism symptoms, behavioral functioning, and health as they age, with some improving and some worsening, a new study shows. This insight may help autistic individuals and their families prepare and plan for the future.
For young adults with Down syndrome, understanding speech is not only related to hearing abilities, but it may also be impacted by cognition.
Dear Waisman Community: For more than 50 years the Waisman Center has been at the intersection of discovery and hope – forging new paths in research and clinical care. One of our strengths is the diversity and breadth of the research, service, training, and outreach efforts that take place under our roof and extend out …
NOTE: Each individual interviewed for this story stated their preference between person-first or identity-first language. The language used reflects the preference of each person. Researchers interviewed use identity-first language in alignment with the preferences of many of those in the autistic community. Who is considered an expert in autism? Or cerebral palsy? Or Down syndrome? …
Title: Congruent gene expression in Alexander disease model mice and human Alzheimer’s disease Legend: (A) A Rank-Rank Hypergeometric Overlap (RRHO) heatmap comparing a composite gene expression portrait of human Alzheimer’s disease (AD, X axis) with transcriptomic changes in hippocampus from Alexander disease model mice (GFAP mutation, Y axis) indicates high matching of up- and downregulated …
Processing neural activity to reconstruct network connectivity is a central focus of neuroscience, yet the spatiotemporal requisites of biological nervous systems are challenging for current neuronal sensing modalities.
Processing neural activity to reconstruct network connectivity is a central focus of neuroscience, yet the spatiotemporal requisites of biological nervous systems are challenging for current neuronal sensing modalities.
Evidence-based assessment pathways inform early detection of cerebral palsy and access to intervention.
Researchers at the Waisman Center are included in a recently launched a new long-term study to observe and track health data of people with Down syndrome from birth to adulthood
