Legend: Left panel: General patterns of [11C]PiB binding in participants with Down syndrome (DS). PiB binds to amyloid-β plaques, a neuropathological hallmark of Alzheimer’s disease (AD). The top row shows nonspecific white matter binding. The …
Alzheimer’s disease
Down syndrome helps researchers understand Alzheimer’s disease
The link between a protein typically associated with Alzheimer’s disease and its impact on memory and cognition may not be as clear as once thought, according to a new study from the University of Wisconsin-Madison’s …
Fragile X protein may play role in Alzheimer’s disease
A brain afflicted by severe Alzheimer’s disease is a sad sight, a wreck of tangled neural connections and organic rubble as the lingering evidence of a fierce internal battle.
Discovery may halt progression of Alzheimer’s
In a finding that may cause a dramatic shift in the way scientists and researchers search for a therapy for Alzheimer’s disease, a team of researchers led by Jeff Johnson, an associate professor at the School of Pharmacy, has discovered that increased expression of a protein called transthyretin in the brain appears to halt the progression of the disease.