Year: 2018

Scientists discover cause of aging-related disease in mice, then reverse its symptoms

In a study published in Aging Cell, researchers at the University of Wisconsin–Madison show that mice making too much of a human protein called AT-1 show signs of early aging and premature death, which are also symptoms of the human disorder progeria. Researchers were able to reverse the signs of accelerated aging and early death …

Brittany G. Travers, PhD – Slide of the Week

The current study investigated the relation between postural balance and performance of daily living skills (DLS) in youth with autism spectrum disorder (ASD). Fifty-two youth with ASD (6–17 years; IQ ≥ 67) completed standardized balance testing and parent-reported DLS measures.

Ender Tekin, PhD – Slide of the Week

Children who cannot effectively read print because of a visual, physical, perceptual, developmental, cognitive or learning disability, are considered to have a print disability.

Childhood stress leaves lasting mark on genes

How does stress put some children at risk of psychiatric disorders when they grow up? To find out, researchers compared their genomes to those of kids whose childhoods were relatively tranquil.

John Svaren, PhD – Slide of the Week

Our goal was to define the genetic cause of the profound hypomyelination in the taiep rat model and determine its relevance to human white matter disease.

Masatoshi Suzuki, DVM, PhD – Slide of the Week

Human induced-pluripotent stem cells are a promising resource for propagation of myogenic progenitors. Our group recently reported a unique protocol for the derivation of myogenic progenitors directly (without genetic modification) from human pluripotent cells using free-floating spherical culture.

Unraveling the mysteries of a rare neurological disorder

Could understanding the ebb and flow of calcium in brain cells provide clues that help researchers develop a treatment for a devastating neurological disease? Rett syndrome, a rare, non-inherited neurological disorder that mostly affects girls and causes severe deterioration in their ability to speak, eat, move and even breathe easily is caused by variations in …

Meet the new director: Qiang Chang, PhD

A cutting-edge scientist and a family chef as well as a former professional chess player…meet Qiang Chang, the next director of the Waisman Center! Qiang Chang, a professor of medical genetics and neurology and Waisman Center investigator, began his tenure as the next director of the Waisman Center on July 1. The transition to center …

Using artificial intelligence for a big impact on neurodevelopmental research

Arezoo Movaghar earned her master’s degree in computer science and artificial intelligence. She built models based on the plentiful data found in medical records. So, when she came to UW–Madison as a PhD student and joined a research group, it surprised Movaghar to find out just how much data researchers in other fields collect.

Study points researchers toward new therapies for fragile X syndrome

By Adityarup “Rup” Chakravorty New insights into the molecular machinations behind fragile X syndrome, the most common inherited intellectual disability, may help researchers develop potential therapies. Fragile X is a genetic condition that affects one in 4,000 males and one in 6,000 females. It’s linked to variations in the gene that makes a protein called …