Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Wargowski, after three decades of providing exceptional patient care to hundreds of patients in the Medical Genetics Clinics at Waisman, is retiring at the end of June.
Dendritic spines, the mushroom-shaped extensions along dendritic shafts of excitatory neurons, are critical for synaptic function and are one of the first neuronal structures disrupted in neurodevelopmental and neurodegenerative diseases.
14 undergraduate students from the labs of Waisman Center investigators and affiliates were awarded the Hilldale Undergraduate/Faculty Research Fellowship, which includes a stipend for students and for their research advisors. Students will have the opportunity to work on their own research project in collaboration with their faculty advisor. Congratulations to award recipients: Evelyn Anton (Margarita …
Kathleen Kastner, MD, associate professor, Division of Developmental Pediatrics and Rehabilitation Medicine, and developmental behavioral pediatrician in the Waisman Center's Autism and Developmental Disabilities Clinic and Newborn Follow-Up Clinic, was selected for a 2024 University of Wisconsin School of Medicine and Public Health (SMPH) Dean’s Teaching Award.
Fragile X messenger ribonucleoprotein 1 protein (FMRP) deficiency leads to fragile X syndrome (FXS), an autism spectrum disorder.
To the naked eye, they look like tiny blobs free floating in a pink liquid. Under a light microscope, they look similar. But organoids, a 3-D mini version of an organ grown in a lab, may contain invaluable information about how the human brain develops.
DNA libraries generated from 235 post mortem human brain samples were sequenced using 150 bp, paired end Illumina chemistry to a desired depth of 30X coverage. Reads were aligned to either the linear GRCh38 alt-free reference genome, the linear telomere to telomere hs1 reference genome, or the draft human pangenome.
Feeding challenges seen in an autistic child’s first few years can help predict the type and severity of feeding challenges the child may experience later on.
Genotypes are strongly associated with disease phenotypes, particularly in brain disorders. However, the molecular and cellular mechanisms behind this association remain elusive.
We want to better understand how autistic children with and without attention-deficit/hyperactivity disorder (ADHD) differed in their motor skills, sensory features, and daily living skills.
