Seth Pollak: A career dedicated to understanding child emotion

The fun decals on the colorful walls and the cheerful environment gives it away, the third floor of the Waisman Center is dedicated to children. This space is where Seth Pollak, PhD, has spent most of his career studying child emotion, and how early life experiences shape the brain during development.

New machine learning algorithm improves estimation and integration of single-cell data

Like a game of Wheel of Fortune, where you have to fill in missing letters to guess the hidden phrase, analyzing data sometimes requires estimating missing data points by relying on available information in order to get the full picture of what’s being studied.

We need to know STAT: Mechanisms behind GFAP accumulation in Alexander disease involve transcription factor STAT3.

The hallmarks of Alexander disease, aggregation of misfolded GFAP proteins and dysregulation of brain cells called astrocytes, may be stopped and reversed in rodent models with the inactivation of the transcription factor STAT3.

Building bridges between disciplines: Marsha Mailick’s interdisciplinary research and leadership at the Waisman Center

Multiple angles of vision all focused on a common question is what attracted Marsha Mailick, PhD, emeritus vice chancellor for research and graduate education at the University of Wisconsin-Madison, to the Waisman Center more than 35 years ago.